Epicutis Hydrobiome Serum

Vendor:Epicutis

Hydrobiome Serum

$165.00

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Balances The Skin Microbiome

Epicutis Hydrobiome Serum is designed to improve overall skin health by rebalancing the skin's microbiome. Instead of disrupting the skin, it works to regulate how skin responds to stress, helping reduce visible irritation and support a clearer, more stable complexion over time.

Laziza K
"Sometimes the skin just starts acting out and you don’t really know why - breakouts, texture, redness, barrier issues, or it just feels reactive and nothing seems to work. A lot of the time, that can be a microbiome imbalance. Repairing the barrier alone isn’t always enough, which is why supporting the skin’s microbiome matters too. Epicutis Hydrobiome Serum is one of the clinically evaluated serums I’ve seen help bring the skin back into balance while still supporting clearer, more stable skin over time."
Laziza K
Head Esthetician & Founder
Closeup of Laziza from LAZ Skincare holding up a bottle of Epicutis Hydrobiome Serum

Strengthens A Compromised Skin Barrier

The formula supports barrier integrity by combining antioxidant protection with hydration-focused ingredients. This helps reinforce the skin’s natural defenses, allowing it to better retain moisture, resist external stressors, and maintain a healthier, more resilient surface.

TCP

Helps balance the microbiome, calm inflammation, and reduce the appearance of blemishes.

TPNa

A water-soluble vitamin E derivative that provides antioxidant protection and helps strengthen the skin barrier.

Sodium Hyaluronate

Helps instantly boost the skin’s moisture level for better hydration and comfort.
Laziza from LAZ Skincare holding a bottle of Epicutis Hydrobiome Serum up to her face

Calms Inflammation And Reduces Redness

Targeted ingredients help regulate inflammatory pathways and limit the overgrowth of acne-associated bacteria without stripping the skin. This approach helps visibly reduce redness and discomfort while supporting a calmer, more balanced skin environment.

Same Day Shipping

We ship all orders every day, so your skincare never has to wait. With fast, daily fulfillment, you’ll get your products quickly—before you run out or miss a step in your routine.
Laziza from LAZ Skincare demonstrating the texture and application of Epicutis Hydrobiome Serum on her hand

Ideal For Reactive, Blemish-Prone, Or Barrier-Damaged Skin

Epicutis Hydrobiome Serum is well suited for skin that feels reactive, acne-prone, or barrier-damaged. Its lightweight, fast-absorbing texture makes it easy to use daily, especially for those looking to support long-term skin health without relying on aggressive or sensitizing treatments.

Frequently Asked Questions

Who is Epicutis Hydrobiome Serum best for?

Epicutis Hydrobiome Serum is best for skin that feels reactive, acne-prone, or consistently irritated. It’s especially helpful for anyone dealing with redness, barrier damage, or skin that doesn’t tolerate traditional actives well.

How does Epicutis Hydrobiome Serum support the microbiome?

Epicutis Hydrobiome Serum helps regulate how the skin responds to inflammation and bacteria rather than stripping or disrupting it. This allows the skin to rebalance itself, which is key for long-term clarity and stability.

Will this help with breakouts?

Yes, but in a different way. Epicutis Hydrobiome Serum reduces the triggers behind breakouts—like inflammation and imbalance—rather than aggressively drying or exfoliating the skin.

Can I use Epicutis Hydrobiome Serum on sensitive or post-treatment skin?

Yes. Epicutis Hydrobiome Serum is a strong option for compromised or post-procedure skin because it focuses on calming, repairing, and supporting the barrier without adding stress.

Do I still need other serums with Epicutis Hydrobiome Serum?

It depends on your skin goals. Epicutis Hydrobiome Serum can act as a foundation for skin health, and in many cases, it helps your skin tolerate other treatments better rather than replacing them entirely.

Genuine Products

We are proud to be an Authorized Epicutis Retailer, using the exact same products every day on clients in our NYC skincare clinic. Every product you receive is 100% authentic and factory-sealed. All items are shipped directly from our environmentally controlled space to preserve their quality and efficacy.

How to Use Hydrobiome Serum

Apply 1–2 pumps to clean, dry skin and gently press into the face and neck. Use morning and evening before heavier serums or moisturizers. Can be layered under actives or used on its own when the skin feels reactive or out of balance.

Full Ingredients List

Water, Propanediol, Pentylene Glycol, Glycerin, Disodium Tetramethylhexadecenylcysteine Formylprolinate, Sodium Tocopheryl Phosphate, Sodium Hyaluronate, Sodium Phytate, Carbomer, and Potassium Hydroxide.

Results Vary by Individual

The skincare benefits described are based on the product’s intended use and active ingredients, but individual results can vary. Factors such as skin type, condition, lifestyle, and consistent use all influence outcomes. This information is not a substitute for professional advice. Always follow usage directions and consult a skincare professional for personalized recommendations.

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