Smooths Deep Lines Without Needles

InterFuse Intensive Treatment LINES is designed to target and visibly soften deep expression lines and wrinkles without injections. Using advanced delivery technology, it works exactly where you need it most, leaving your skin looking smoother and more refreshed over time. Apply it as the first step after cleansing, before serums or moisturizer.

Laziza S

"Some clients use SkinBetter InterFuse Intensive Treatment LINES as an alternative to fillers or Botox. We recommend it for improving deep lines that have already formed. It works beautifully on elasticity and stubborn wrinkles, especially when paired with AlphaRet Overnight Cream or Clearing Serum. Pro tip: it’s amazing on lips, upper lip, and under the eyes."

Laziza S
Head Esthetician & Founder
Closeup of Laziza from LAZ Skincare holding up a bottle of SkinBetter Science InterFuse Intensive Treatment LINES

Plumps and Hydrates for a Softer Look

This formula draws and locks in moisture to help plump the skin, reducing the appearance of lines. Its high-grade hyaluronic acid, a naturally occurring humectant, deeply hydrates while supporting the skin barrier. The multi-layer hydration effect keeps skin supple, helping those stubborn creases look less noticeable over time.

Hyaluronic Acid

Naturally occurring humectant used to deeply hydrate, plump, and support the skin barrier.

Peptides

Short chains of amino acids that help signal the skin to repair, firm, and rebuild itself.

Amino Acids

Building blocks of proteins, including collagen, elastin, and keratin used for their ability to hydrate, repair, and protect the skin barrier.

Laziza from LAZ Skincare holding a bottle of SkinBetter Science InterFuse Intensive Treatment LINES up to her face

Helps Support Skin’s Structure

A blend of line-softening peptides and skin-supporting nutrients works to keep skin firm and resilient. With regular use, it helps maintain a smoother texture while working alongside your natural collagen for lasting benefits. Amino acids, the building blocks of collagen, elastin, and keratin, help hydrate, repair, and protect the skin barrier.

Laziza from LAZ Skincare demonstrating the texture and application of SkinBetter Science InterFuse Intensive Treatment LINES on her hand

Targets Problem Areas With Precision

Perfect for crow’s feet, forehead lines, smile lines, and lip creases, this formula is meant for focused application. It fits seamlessly into any anti-aging routine and pairs well with in-office procedures for enhanced results. It also works beautifully on the upper lip and under the eyes, especially alongside AlphaRet Overnight Cream.

Clinical Results

  • 31%

    improvement in the targeted area of crow's feet after 8 weeks

  • 23%

    improvement in the targeted area of forehead lines after 8 weeks

  • 68%

    of patients demonstrated improvement in nasolabial folds after 8 weeks

Products To Pair With InterFuse Intensive Treatment LINES

AlphaRet Overnight Cream

SkinBetter Science

AlphaRet Overnight Cream
Retinoid and AHA blend that reduces wrinkles and smooths skin with minimal irritation.
5.0
From $76.00
Laziza S
“Apply AlphaRet at night after InterFuse Treatment LINES for a complete anti-aging routine that combines targeted line-filling with retinoid-powered collagen renewal and resurfacing.”
Laziza S
Founder & Head Esthetician
Choose options
Alto Advanced Defense and Repair Serum

SkinBetter Science

Alto Advanced Defense and Repair Serum
Antioxidant-rich serum that defends against oxidative stress and improves tone and texture.
4.9
From $100.00
Laziza S
“Apply Alto Advanced every morning to protect against the environmental and internal oxidative stress that accelerates the formation of the lines InterFuse Treatment LINES is working to correct.”
Laziza S
Founder & Head Esthetician
Choose options

Frequently Asked Questions

How is this different from a traditional hyaluronic acid serum?

Unlike general HA serums, InterFuse Intensive Treatment LINES uses injectable-grade hyaluronic acid with a patented delivery system for precise application. It’s targeted specifically for deep expression lines rather than overall facial hydration.

Can this replace in-office injectables?

While it can enhance and prolong the effects of professional treatments, it is not a substitute for dermal fillers. Instead, it works alongside in-office procedures or as a non-invasive option for those not ready for injections.

When will I see results?

Some users notice a softer look to expression lines within hours of application due to immediate plumping from hyaluronic acid. Continued use over several weeks helps improve skin smoothness and resilience for longer-lasting results.

Is it safe for use around the eyes and lips?

Yes; this product is formulated to be applied to delicate areas such as crow’s feet and upper lip lines. Avoid direct contact with the eyes, and apply with gentle tapping motions for optimal absorption.

What’s the difference between InterFuse Intensive Treatment LINES and InterFuse Treatment EYE?

InterFuse LINES is designed as a targeted treatment for deep wrinkles and expression lines, like those on the forehead, around the mouth, or between the brows. InterFuse EYE, on the other hand, is formulated specifically for the delicate eye area to address concerns like puffiness, dark circles, dryness, and fine lines without causing irritation.

Authentic Products

We are proud to be an Authorized SkinBetter Science Retailer. Every product you receive is 100% authentic and factory-sealed. All items are shipped directly from our environmentally controlled space to preserve their quality and efficacy. 

How to Use InterFuse Intensive Treatment LINES

Apply it as the first step after cleansing and before serums or moisturizers. This ensures the high-grade hyaluronic acid and peptides reach the skin without interference from other products, maximizing line-smoothing effects.

Full Ingredients List

Aqua/Water, C12-15 Alkyl Benzoate, Glycerin, PEG-16 Macadamia Glycerides, Dimethicone, Acetyl Glucosamine, Alcohol Denat., Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Citrate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Glycine, Hydroxyproline, Proline, Acetyl Hexapeptide-8, Hexapeptide-48 HCl, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Acetylated Hyaluronate, Pisum Sativum (Pea) Extract, Glycine Soja (Soybean) Seed Extract, Glucosamine HCl, Ophiopogon Japonicus Root Extract, Bambusa Vulgaris Leaf/Stem Extract, Hydrolyzed Lupine Protein, Oleic Acid, Sorbitan Isostearate, C18-36 Acid Glycol Ester, PEG-7 Trimethylolpropane Coconut Ether, Sorbitan Laurate, Hexylene Glycol, Polyisobutene, C18-36 Acid Triglyceride, Carbomer, Acrylates Copolymer, Citric Acid, Caprylyl Glycol, Ethylhexylglycerin, Potassium Sorbate, Phenoxyethanol.

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