
iS Clinical

“Retinol and peels both resurface, so we space them out rather than stacking them. Use the Active Peel System on the nights you skip your retinol and your texture keeps improving comfortably.”

Retinol+ Emulsion 0.3
"Our clients find the texture of the Retinol Emulsion 0.3 to be unique, it offers gentle but powerful results, minimizing irritation while promoting smoother, clearer skin. It feels like a moisturizer, providing hydration while helping reduce fine lines and uneven texture. Gets absorbed very easily and doesn't feel heavy at all. You can get started with 2-3 times a week."
Laziza S
Retinol
Vitamin A derivative that promotes skin renewal, increases collagen production, and improves overall skin tone and texture.
Ectoin
Powerful stress-protection molecule offering anti-inflammatory, barrier-supportive, and moisture-retaining benefits
Vitamin C
Potent antioxidant that protects the skin from free radical damage, supports collagen production, and improves overall skin tone and radiance.

iS Clinical

“Retinol and peels both resurface, so we space them out rather than stacking them. Use the Active Peel System on the nights you skip your retinol and your texture keeps improving comfortably.”

Plated

“Retinol+ smooths and brightens while Intense Serum supports repair underneath it. Running both means your skin gets the resurfacing benefit with exosome support working alongside it the whole way.”

Lactic acid exfoliates and hydrates at the same time, which makes it the AHA for dry and easily irritated skin. Here is how it compares to glycolic and how to use it.

Peptides tell your skin cells to build collagen, and they do it without any irritation. Here is what the different types actually do and how to read a peptide label.

Retinoids build collagen, clear pores and fade pigment, with decades of research behind them. Here is how to read the labels and how to start without giving up in week three.

Sodium hyaluronate is the salt form of hyaluronic acid, and usually the better choice. Here is why it is on the back of the bottle when the front says something else.

Vitamin C intercepts the daily damage from sun and pollution, fades dark patches and is required for your skin to build collagen. Here is how it works and which form suits your skin.

Ectoin holds water steady around your skin cells, so skin that reacts to wind, heat, flights and city air stays calm. Here is what the eczema trials found and how to use it.

Glutathione is the antioxidant your own cells make. What it does about everyday damage and uneven tone, and how to choose a product that still works when you open it.

Vitamin E protects the fatty part of your skin barrier from sun and pollution damage, and it works best paired with vitamin C. Here is why that pairing matters, and why the research does not back putting it on a scar.

Squalane is the stable version of an oil your skin already makes, and it suits dry, reactive and acne-prone skin without clogging pores. Here is the one-letter difference that matters on a label and where it belongs in your routine.

Shea butter softens dry skin and slows the water loss that leaves it tight and flaky. Here is how it works, what the eczema research found and what to know about nut allergies.

Glycerin draws water into the outer layer of your skin and helps your barrier recover. Here is how it differs from the oils in your moisturizer, and what it does in very dry air.
Retinol+ Emulsion 0.3 stands out because of its advanced delivery system. The retinol is encapsulated in bioidentical lipids, which allows it to penetrate deeply and release slowly. This minimizes irritation while maximizing results. It also includes anti-inflammatory ingredients and IS Clinical’s Extremozyme® technology, which protects against environmental aggressors.
Yes, this 0.3% strength is an excellent entry point for those new to retinol or with sensitive skin. Its encapsulated delivery ensures that it works gradually, reducing the risk of redness and peeling. That said, it's still potent, start with 2–3 nights per week and increase as tolerated.
It depends on your routine. Retinol should not be layered with strong exfoliants (like AHAs or benzoyl peroxide) unless directed by a professional. However, it works well with hydrating and barrier-repair products, antioxidants, and gentle cleansers. Always follow with SPF in the morning, as retinol increases sun sensitivity.
Most users begin to see smoother texture and more even tone within 4–6 weeks. Fine lines, pigmentation, and breakouts may take 8–12 weeks to show noticeable improvement. With consistent use, skin becomes brighter, firmer, and more resilient over time.
Start slow, 2 to 3 nights per week is ideal for most. Once your skin adjusts, you can increase frequency to nightly use if tolerated. Listen to your skin; if you experience redness or dryness, reduce usage and buffer with a gentle moisturizer.
We are proud to be an Authorized iS Clinical Retailer. Every product you receive is 100% authentic and factory-sealed. All items are shipped directly from our environmentally controlled space to preserve their quality and efficacy.
Apply 2-3 pumps to clean skin, smoothing evenly over face and neck at night every 3 days for 3 weeks. If well tolerated, apply every 2 days or as directed.
Water/Aqua/Eau, Glycerin, Squalane, Pentylene Glycol, Sodium Hyaluronate, Ectoin, Glyceryl Citrate/ Lactate/ Linoleate/ Oleate, Polyglyceryl-4 Cocoate, Polyglyceryl-3 Cocoate, Glyceryl Caprylate, Chlorella Vulgaris Extract, Tocopherol, Butylene Glycol, Bakuchiol, Triethanolamine, Carbomer, Retinol, Phragmites Communis Extract, Poria Cocos Extract, Oryza Sativa (Rice) Bran Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Phosphatidylcholine, Propanediol, Butyrospermum Parkii (Shea) Butter, Polysorbate 20, Caprylic/Capric Triglyceride, Lecithin, Lactic Acid, Polysorbate 40, Helianthus Annuus (Sunflower) Extract, Phenoxyethanol, Polyacrylamide, C13-14 Isoalkane, Laureth-7, Tripeptide-1, Dextran, Ascorbic Acid, Colloidal Gold, Glutathione, Panthenol, Heptyl Undecylenate, C13-16 Isoalkane, Dipotassium Glycyrrhizate, Bidens Pilosa Extract, Elaeis Guineensis (Palm) Oil, Gossypium Herbaceum (Cotton) Seed Oil, Linum Usitatissimum (Linseed) Seed Oil, Glycine Soja (Soybean) Extract, Sodium Hydroxide, Disodium EDTA, Phenylpropanol, Ethylhexylglycerin, Caprylyl/ Capryl Glucoside, Diisopropyl Adipate, Triethyl Citrate, Xanthan Gum, Sorbitol, Fragrance/Parfum