Many of the fine lines and much of the dullness you notice in your forties began years earlier, on ordinary days in the sun. Resveratrol, an antioxidant found in grapes and berries, helps protect your collagen and your glow from that daily damage.
The short answer
Resveratrol is an antioxidant, an ingredient that neutralizes the unstable molecules sun creates in your skin. It also calms the inflammation sun sets off, which helps you keep the collagen you have. In the small human studies, fine lines, tone and radiance improved with steady, daily use. Expect gradual, protective change rather than a quick one.
What it does
Resveratrol is an antioxidant, an ingredient that neutralizes the unstable molecules sun creates in your skin. It also calms the inflammation sun sets off, which helps you keep the collagen you have. In the small human studies, fine lines, tone and radiance improved with steady, daily use. Expect gradual, protective change rather than a quick one.
Why skin loses its collagen and its glow
Sun creates unstable molecules in your skin, often called free radicals, and pollution adds more. Each of these molecules is missing an electron and takes one from whatever is nearby, including your collagen, the protein that keeps skin smooth and springy.
Your skin makes its own antioxidants, and on a sunny day they can be outnumbered. The damage that gets through sets off inflammation, one of the root causes of aging skin. Inflammation switches on enzymes that break collagen down, which is how fine lines form. It can also prompt extra pigment and leave the surface uneven, and an uneven surface scatters light instead of reflecting it evenly, which is a large part of why skin looks dull.
How resveratrol works
Resveratrol works on that damage in two ways. It neutralizes unstable molecules directly, by giving up an electron of its own, which stops them taking one from your collagen. It also prompts your cells to make more of their own antioxidant enzymes, which means it strengthens the defenses your skin already has.
In human skin cells grown in a dish, resveratrol reduced the enzyme that breaks collagen down after UV exposure. In mice, resveratrol applied topically before UV reduced swelling, inflammation and oxidative damage.
There is a secondary benefit for tone. In laboratory work, resveratrol slows tyrosinase, the enzyme pigment cells use to make melanin. It works on excess pigment, not your natural skin tone.
Where resveratrol comes from
Plants make resveratrol to defend themselves against stress such as UV light and fungal infection. More than 70 plant species contain it, including grapes, berries, peanuts and a plant called Japanese knotweed, one of the most concentrated sources.
The resveratrol in skincare is extracted from plants such as Japanese knotweed or made through fermentation, and both routes give the same molecule.
What the research shows
The human evidence on resveratrol applied topically is small, and much of it comes from formulas that combine resveratrol with other antioxidants.
The largest study is a 2025 randomized, placebo-controlled trial in about 120 women over 40, who used a 1.5 percent resveratrol cream, a resveratrol supplement, both, or neither for eight weeks. Only the group using both saw wrinkles improve more than the placebo group did, and both groups using the cream saw pigmentation fade more than the placebo group did. The company that developed the ingredients funded it.
A smaller 12-week study of a night cream with 1 percent resveratrol, vitamin E and baicalin, another plant antioxidant, found improvements in fine lines, firmness, radiance and uneven pigment. Most of the researchers worked for the manufacturer, there was no placebo group, and part of the result belongs to the other two antioxidants.
What to look for on a label
The names it goes by
Look for resveratrol or trans-resveratrol, the form used in the studies. Those studies used 1 to 1.5 percent.
Why packaging matters
Resveratrol is sensitive to light. In one laboratory study, a cream lost about a third of its resveratrol under light that mimics the sun, and tiny capsules made of fats cut that loss to about a fifth. Opaque packaging and an encapsulated formula help keep it working.
Where it sits in your routine
Most resveratrol products are serums, which go on after cleansing and before your moisturizer. If yours is a cream, that is your moisturizer step.
What works best with resveratrol
Antioxidants work well as a team, because each antioxidant covers a different part of your skin. Vitamin C works in the watery parts and vitamin E in the oily parts, and the two protected skin from UV better together than either did alone. Ferulic acid, a plant antioxidant, makes vitamins C and E more stable, and in a study on pig skin it doubled the protection the pair gave. Resveratrol adds another antioxidant to that team.
Niacinamide works well alongside resveratrol, because it supports your barrier and evens tone, which are different jobs. A retinoid fits too: resveratrol helps protect the collagen you have, while a retinoid prompts your skin to build more.
Sunscreen every morning, reapplied through the day. Resveratrol neutralizes some of what UV creates in your skin, and it does not block UV, which means it works alongside sunscreen rather than in place of it.
Common questions
Can I get resveratrol from red wine?
No, not in an amount that would help your skin. Red wine contains about two milligrams of resveratrol per liter on average, while the supplement in the 2025 trial supplied 150 milligrams a day.
Does a resveratrol supplement help?
Yes, it can, based on the research available. Taken by mouth, resveratrol is well absorbed, though your body quickly converts most of it. In the 2025 trial, the group taking the supplement with the cream saw the clearest change in wrinkles.
A supplement cannot deliver a predictable amount to your skin, because your body distributes it by its own priorities. Applying resveratrol topically is how you control the amount on your face, and doing both is reasonable. Speak to your doctor before starting a supplement, especially if you take other medication.
Can I use it in the morning?
Yes. Many resveratrol products are designed for night because light breaks resveratrol down, and others are made to stay stable by day. Follow what the manufacturer recommends, and apply it before your sunscreen.
How soon will I see something?
The protection starts on day one, and you will not see that part. Changes in fine lines, tone and radiance were measured at eight to twelve weeks, which makes three months a fair trial. Photograph your skin on day one in natural daylight, in the same spot, then every four weeks. Week four is when many people decide nothing is happening, and it is the moment to keep going.
Is it safe in pregnancy?
Resveratrol has not been studied in pregnancy, and skincare ingredients are almost never tested on pregnant people. Vitamin C and niacinamide are generally considered safe in pregnancy, and most retinoids are avoided. Check with your OB or midwife before starting resveratrol or a resveratrol supplement.
How to use it
- Use resveratrol every day, once or twice a day as the manufacturer recommends. Using it consistently is what gives you results.
- Apply it to clean, dry skin after cleansing, then follow with your moisturizer.
- Close the cap straight after use and keep the product out of direct sunlight. Follow the storage directions on your packaging.
- Broad spectrum SPF 30 or higher every morning, reapplied through the day.
- Give it three months before you judge the result.
Evidence and sources
- Rao A, Briskey D, Roche G, Tremblay A, Da Silva Pinto M, Tompkins TA. Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial. Frontiers in Aging, 2025;6:1727244. The four-group trial of a 1.5 percent cream and a 75 mg twice-daily supplement; funded by the company that developed both, with authors employed by it and by the company that later acquired it. Read the study
- Farris P, Yatskayer M, Chen N, Krol Y, Oresajo C. Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin E for treatment of mild to moderately photodamaged skin. Journal of Drugs in Dermatology, 2014;13(12):1467-1472. The 12-week combination study; most authors were from the manufacturer. Read the study
- Farris P, Krutmann J, Li YH, McDaniel D, Krol Y. Resveratrol: a unique antioxidant offering a multi-mechanistic approach for treating aging skin. Journal of Drugs in Dermatology, 2013;12(12):1389-1394. Review covering plant sources, its role in plants, and how resveratrol raises the skin's own antioxidant enzymes. Read the review
- Na JI, Shin JW, Choi HR, Kwon SH, Park KC. Resveratrol as a multifunctional topical hypopigmenting agent. International Journal of Molecular Sciences, 2019;20(4):956. Review of how resveratrol slows tyrosinase directly and indirectly. Read the review
- Lee J, Oh J, Song D, Lee M, Hahn D, Boo YC, Kang NJ. Acetylated resveratrol and oxyresveratrol suppress UVB-induced MMP-1 expression in human dermal fibroblasts. Antioxidants, 2021;10(8):1252. The skin cell research on the collagen-breaking enzyme. Read the study
- Afaq F, Adhami VM, Ahmad N. Prevention of short-term ultraviolet B radiation-mediated damages by resveratrol in SKH-1 hairless mice. Toxicology and Applied Pharmacology, 2003;186(1):28-37. The mouse research on UV damage. Read the study
- Scalia S, et al. Enhancement of trans-resveratrol photostability by encapsulation in lipid microparticles: in vitro and in vivo studies. Pharmazie, 2017;72(4). The laboratory study on light losses in a cream. Read the study
- Lin JY, Selim MA, Shea CR, Grichnik JM, Omar MM, Monteiro-Riviere NA, Pinnell SR. UV photoprotection by combination topical antioxidants vitamin C and vitamin E. Journal of the American Academy of Dermatology, 2003;48(6):866-874. Pig skin study: the combination protected better than either vitamin alone. Read the study
- Lin FH, Lin JY, Gupta RD, et al. Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 2005;125(4):826-832. Pig skin study: adding ferulic acid stabilized vitamins C and E and roughly doubled their UV protection. Read the study
- Walle T, Hsieh F, DeLegge MH, Oatis JE Jr, Walle UK. High absorption but very low bioavailability of oral resveratrol in humans. Drug Metabolism and Disposition, 2004;32(12):1377-1382. How the body absorbs and converts resveratrol taken by mouth. Read the study
- Stervbo U, Vang O, Bonnesen C. A review of the content of the putative chemopreventive phytoalexin resveratrol in red wine. Food Chemistry, 2007;101(2):449-457. Source for the average resveratrol content of red wine.
- Krutmann J, Liu W, Li L, et al. Pollution and skin: from epidemiological and mechanistic studies to clinical implications. Journal of Dermatological Science, 2014;76(3):163-168. How pollution adds to oxidative stress in skin. Read the review
A note on the evidence. The antioxidant activity of resveratrol is well established, and its effects on collagen, UV damage and the pigment enzyme come from cells and mice. In people, there is one developer-funded placebo-controlled trial and one small manufacturer-run study of a combination formula. Both found improvements, which is real and not the same as long-term, independent data.
Products with Resveratrol
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Acne-safe peptide and antioxidant serum that supports firmness, softens fine lines and defends skin.
Once my clients finish their acne program, I may recommend introducing acne-safe anti-aging if it’s something they need. The Antioxidant Peptide Face Serum is a great, budget-friendly option because as we lose collagen and elastin each year and the skin’s healing slows, peptides help support repair and resilience. It can be layered with Mandelic or HydraRemedy, but I only suggest adding it if anti-aging is a priority.
Laziza SFounder & Head Esthetician Repair, Firm, and Defend
Face Reality Antioxidant Peptide Face Serum is a lightweight serum for acne-safe anti-aging. Palmitoyl tripeptide-38 and a copper complex support the repair and collagen your skin makes on its own, while a spin trap antioxidant and resveratrol neutralize the free radicals that drive inflammation and visible aging. Apply one pump over a clean face, or only where you need it.
Made for Acne-Prone Skin, but Benefits All
This serum was developed with reactive, acne-prone clients in mind. It is non-comedogenic and fragrance-free, and glycerin draws water into your skin to keep it hydrated. Resveratrol, an antioxidant found naturally in red grapes, is included here as a ferment extract, and cyclodextrin helps keep the antioxidants stable. It is designed to fit into an acne routine without clogging pores.
Anti-Aging Without the Aggression
Palmitoyl tripeptide-38 signals your skin to build more collagen, which softens the look of fine lines and supports firmness over time. That makes it a good fit if your skin is reactive or you would rather not use strong exfoliants. The spin trap antioxidant captures free radicals before they can damage that collagen. It can also be layered with Mandelic Serum or HydraRemedy.
Lightweight, Layerable, and Travel-Friendly
The Antioxidant Peptide Face Serum absorbs quickly into the skin and pairs well with other Face Reality products. Use it morning or night between your cleanser and moisturizer to add hydration and repair support. It is lightweight enough for oily skin, and glycerin with a light emollient keeps it comfortable on dry skin too.
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Daily serum that firms, smooths fine lines and brightens by working on glycation.
If you are looking for a serum that helps even skin tone, protect against environmental aging, restore glow, and minimize fine lines, Revision D·E·J Daily Boosting Serum does all of those things. It works on multiple signs of aging at once without making the routine complicated. It's one of Revisions bestsellers for a reason.
Laziza SFounder & Head Esthetician Daily Serum That Energizes Skin Cells
Revision Skincare D·E·J Daily Boosting Serum is a multi-tasking daily serum formulated around patented Sunflower Sprout Extract Technology that boosts cellular energy and allows skin to function in a more youthful way. It visibly improves firmness, fine lines, texture, radiance, and uneven tone while supporting the microbiome and defending against environmental stress. Suitable for all skin types.
Addresses Glycation, a Common Cause of Aging
Glycation occurs when sugar molecules bind to collagen and elastin, making them stiff and brittle over time. It is a primary driver of fine lines, loss of firmness, and dullness. D·E·J Daily Boosting Serum contains patented Sunflower Sprout Extract and Iris Florentina Root Extract to reduce glycation and visibly improve skin quality, firmness, and radiance with daily use.
Firms Skin and Reduces Fine Lines
When cellular energy declines and glycation accumulates, skin loses some of its ability to maintain firmness and renew itself efficiently. D·E·J Daily Boosting Serum boosts cellular energy, supports the dermal-epidermal junction, and visibly improves fine lines and elasticity. In clinical studies, texture and fine lines visibly improved in as early as seven days and continued improving through twelve weeks.
Brightens and Evens Skin Tone
Dullness, uneven tone, and the lingering effects of sun damage all respond to the daily antioxidant protection and microbiome support this serum delivers. THD Ascorbate, a stable form of vitamin C, brightens and defends against the environmental damage behind discoloration, and Resveratrol adds antioxidant support. For extra brightening, Revision recommends pairing D·E·J Daily Boosting Serum with C+ Correcting Complex 30%.
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Moisturizer and mask that calms, hydrates, and supports reactive skin without heaviness.
If your skin feels overheated, reactive, dehydrated, or irritated, Hale & Hush Hydrate Gel gives hydration and calming support without feeling heavy or greasy. I recommend it a lot for rosacea-prone, acne-prone, and post-treatment skin because it feels lightweight while still keeping the skin comfortable and hydrated. If your skin is very dry, I recommend layering Hale & Hush Vital Lipid Lotion on top or the Rehab Oil. Play with both and see which one works best for you.
Laziza SFounder & Head Esthetician A Lightweight Oil-Free Gel That Calms and Hydrates
Hale and Hush Hydrate Gel is an oil-free gel moisturizer formulated for sensitive, reactive, and inflamed skin that needs hydration without heaviness or congestion. Rich in botanical anti-inflammatory extracts and a fermented resveratrol complex, it soothes and cools skin on contact while delivering antioxidant protection and gentle collagen support. It can also be applied generously as a calming mask. Suitable for all skin types.
Cools and Soothes Inflammation on Contact
Reactive skin that is hot, red, or inflamed benefits from something that works right away. Hush Hydrate Gel cools the skin on application through its lightweight water-based gel texture and a blend of potent botanical anti-inflammatory actives. The effect is immediate and noticeable, making it a reliable choice during a flare-up or whenever skin feels uncomfortable and reactive.
Targets Micro-Inflammation at a Cellular Level
Surface redness is often the visible result of micro-inflammation happening beneath the skin. Hush Hydrate Gel contains a fermented resveratrol complex with a small bioavailable molecule that penetrates deeply into the skin to interrupt inflammatory signaling, support the integrity of skin cells, and promote collagen production from within. It calms what is happening beneath the surface as well as the redness you can see.
Hydrates Without Clogging Pores or Feeling Heavy
If your skin is oily, acne-prone, or reactive, you may want a moisturizer that feels light. Hush Hydrate Gel is oil-free, absorbs immediately, and leaves no residue. Squalane, hyaluronic acid, and glycerin provide genuine hydration that keeps skin comfortable and balanced throughout the day without adding weight or shine, even on acne-prone skin.
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A cooling, calming mask that takes redness down fast and doubles as a leave-on moisturizer for reactive and rosacea-prone skin.
If your skin is red, reactive, or just went through something like a peel, extractions, or a bad flare, Hale and Hush Hush Hydrate Mask can help calm your skin and restore balance. It cools on contact, which our in-clinic clients notice immediately, and it takes redness down fast. What I really like about it is that you can use it as a mask or leave it on as a moisturizer, so it adapts to what your skin needs that day. It pairs especially well with the Bio Relief Powder if redness is your main concern. It's one of the staples for reactive and rosacea-prone skin.
Laziza SFounder & Head Esthetician Instantly Soothes Irritated And Reactive Skin
Hale and Hush Hydrate Mask is designed to calm inflamed, sensitized skin on contact. The lightweight formula helps reduce visible redness and discomfort, making it ideal for skin that feels aggravated, overheated, or reactive to products and procedures. Neem extract supports this calming effect, helping ease irritation so skin feels more comfortable.
Supports Barrier Recovery And Skin Stability
This mask helps reinforce the skin barrier while delivering hydration that supports long-term resilience. By calming inflammation and reducing stress on the skin, it allows the barrier to recover and function more effectively. Squalane provides lightweight hydration and helps support the skin barrier, so skin feels calm, balanced, and comfortable after each use.
Improves Tone And Restores Radiance
Beyond calming benefits, the formula helps improve skin clarity and brightness. With continued use, the complexion appears more even, refreshed, and visibly healthier with a soft, natural glow. Resveratrol ferment extract, an antioxidant, helps protect against environmental stress, and neem extract helps support clearer-looking skin, so your complexion can stay brighter and more balanced.
A Flexible Mask For Changing Skin Needs
Hale and Hush Hydrate Mask can be used as a traditional mask or a leave-on moisturizer when extra support is needed. This versatility makes it especially useful during flare-ups, post-procedure recovery, or periods of increased sensitivity. As a leave-on step, it is built for calming skin that feels overheated or aggravated.
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For use with LED therapy to repair damage and strengthen skin.
L.A.D.R. from Young Goose is the serum I recommend to anyone who uses red light therapy or is thinking about adding it to their routine. Red light therapy is something I find hard to stay consistent with myself. I use it about once a week, so knowing this serum helps me get the most out of each session makes it worth it. If you are the same way, this is what should be on your skin before you use your device.
Laziza SFounder & Head Esthetician Helps Your Red Light Therapy Work Better
Young Goose L.A.D.R. is a light-activated serum formulated specifically for use alongside red and near-infrared light therapy. Applied before a session, it works with the light to enhance the skin's ability to repair UV-induced DNA damage, rebuild collagen, and restore cellular energy. Apply it as the first serum on clean skin before each session.
Repairs Years of Built-Up DNA Damage
UV exposure causes cellular damage that accumulates silently over years, showing up as uneven tone, premature lines, and skin that looks older than it should. L.A.D.R. contains light-activated enzymes that locate and repair this damage directly at the source of the problem. Applied in the morning before sun exposure, it can activate these repair benefits without a device.
Amplifies the Results of Your Red Light Device
Red and near-infrared light therapy stimulates cellular repair and energy production in the skin. L.A.D.R. makes the skin more receptive to that process, improving how it absorbs the light, strengthening collagen-building signals, and supporting the cellular energy needed to carry out repair. Its resveratrol adds antioxidant protection against environmental stress and supports longevity pathways.
Firms Skin and Softens Fine Lines
Young Goose L.A.D.R. Serum is formulated to work synergistically with red light therapy, helping enhance visible results. It supports repair and recovery processes, making it a strong addition to routines focused on advanced skin rejuvenation. Spermidine supports cellular renewal and helps improve skin resilience and structure, while NAD supports the energy processes linked to repair and regeneration.
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A longevity moisturizer that hydrates, protects, and supports aging skin.
Youth Daily from Young Goose is the moisturizer I recommend when someone wants their skin to genuinely improve over time, not just feel good in the moment. It has the same longevity actives as Youth Reset but in a moisturizer format, which makes it easy to stay consistent with. It's a strong standalone moisturizer but it really makes the biggest difference when paired with Youth Reset serum. That said, if you're already using enough serums and want to try Young Goose without adding another step, this is a great place to start - just swap it in place of your current moisturizer.
Laziza SFounder & Head Esthetician A Daily Moisturizer Built for Long-Term Skin Health
Young Goose Youth Daily is a longevity moisturizer that does more than hydrate. It delivers the same advanced cellular actives found in treatment serums in a rich, fast-absorbing cream designed for daily use, working quietly every day to keep skin nourished, protected, and functioning optimally.
Keeps Skin Deeply Hydrated Without Feeling Heavy
Youth Daily works at a deeper level, supporting the skin's ability to retain moisture rather than just adding it temporarily. The formula absorbs quickly, leaves no residue, and works for all skin types including oily and combination skin, keeping skin balanced throughout the day. A thin, even layer as your final step leaves skin feeling comfortable and light.
Protects Against Daily Damage That Ages Skin
UV exposure, pollution, and oxidative damage are leading causes of premature aging. Every day that skin is left unprotected, that damage accumulates. Youth Daily helps defend against this at a cellular level, supporting resilience and the skin's ability to recover from daily environmental exposure. Its resveratrol adds antioxidant protection, and pairing it with sunscreen each morning completes that defense.
Supports Firmness and Prevents Structural Decline
Skin loses firmness gradually as structural proteins break down faster than the body can replace them. Youth Daily supports that repair process daily so the decline happens more slowly, helping skin maintain its structure for longer. It is a preventative moisturizer, and that is the point.
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A longevity serum for skin with several signs of aging at once.
Youth Reset from Young Goose is one of those products I reach for when a client's skin feels like it's plateaued. When the basics are dialed in but something is still missing. What makes it stand out is the combination of longevity ingredients you don't typically see together in one serum. I recommend it to clients in their late 30s and up who are focused on prevention and long-term skin health, not just surface-level correction. It also layers beautifully with other products, including actives.
Laziza SFounder & Head Esthetician Supports Cellular Renewal and Skin Longevity
Young Goose Youth Reset is a multi-functional anti-aging serum for skin dealing with more than one sign of aging at once. It works at a cellular level to support renewal, improve firmness, and restore the luminosity and density that gradually diminish with age. CelVio Spermidine supports cellular renewal and helps improve skin resilience and structure.
Slows Down How Fast Your Skin Ages
As we age, the skin's ability to repair and renew itself slows down. Damage accumulates faster than it can be cleared, and the energy powering repair processes declines. Youth Reset supports the biological mechanisms that keep skin functioning at a younger rate for longer. Resveratrol, an antioxidant, helps protect against environmental stress and supports skin longevity.
Firms and Lifts Skin That Has Lost Structure
Firmness loss occurs when collagen and elastin break down faster than the skin can replace them, showing up as softer, less defined skin around the jawline and cheeks. Youth Reset supports the production of these structural proteins, helping skin regain density and resilience over time.
Fades Dullness and Restores Brightness
When skin looks flat, tired, or gray despite a good night's sleep, it usually signals that cellular turnover has slowed. Dullness is not always a hydration problem. Youth Reset supports the renewal processes that clear dull, damaged cells and restore clarity from within. Used as your first serum, morning, evening, or both, it helps skin look more awake and luminous.
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4.8 4.8 out of 5.0 stars$56.00Face Reality
Antioxidant Peptide Serum 4.8 4.8 out of 5.0 stars
$56.00Acne-safe peptide and antioxidant serum that supports firmness, softens fine lines and defends skin.
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From $140.00Revision
D·E·J Daily Boosting Serum
From $140.00Daily serum that firms, smooths fine lines and brightens by working on glycation.
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5.0 5.0 out of 5.0 stars$40.00Hale & Hush
Hush Hydrate Gel 5.0 5.0 out of 5.0 stars
$40.00Moisturizer and mask that calms, hydrates, and supports reactive skin without heaviness.
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$98.00Hale & Hush
Hush Hydrate Mask
$98.00A cooling, calming mask that takes redness down fast and doubles as a leave-on moisturizer for reactive and rosacea-prone skin.
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$196.50Young Goose
L.A.D.R. Serum
$196.50For use with LED therapy to repair damage and strengthen skin.
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From $88.00Young Goose
Youth Daily
From $88.00A longevity moisturizer that hydrates, protects, and supports aging skin.
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From $109.00Young Goose
Youth Reset
From $109.00A longevity serum for skin with several signs of aging at once.
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